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This course provides an introduction to cellular and population-level systems biology with an emphasis on synthetic biology, modeling of genetic networks,

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2

English

English [CC]

FREE

Description

cell-cell interactions, and evolutionary dynamics. Cellular systems include genetic switches and oscillators, network motifs, genetic network evolution, and cellular decision-making. Population-level systems include models of pattern formation, cell-cell communication, and evolutionary systems biology.

Course content

  • Introduction to the class and overview of the topic Unlimited
  • Input Function, Michaelis-Menten Kinetics, and Cooperativity Unlimited
  • Autoregulation, Feedback and Bisytability Unlimited
  • Synthetic Biology and Stability Analysis In The Toggle Switch Unlimited
  • Oscillatory Genetic Networks Unlimited
  • Graph Properties of Transcription Network Unlimited
  • Feed Forward Loop Network Motif Unlimited
  • Introduction to Stochastic gene Expression Unlimited
  • Stochastic Modeling Unlimited
  • Life at Low Reynolds Number Unlimited
  • Robustness and Bacterial Chemotaxis Unlimited
  • Robustness In Development And Pattern Formation Unlimited
  • Microbial Evolution Experiments and Optimal Gene Circuit Design Unlimited
  • Evolution in Finite Populations Unlimited
  • Clonal Interference and the Distribution of Beneficial Mutations Unlimited
  • Fitness Landscapes and Sequence Spaces Unlimited
  • Evolutionary Games Unlimited
  • Survival In Fluctuating Environments Unlimited
  • Parasites the Evolution of Virulence and Sex Unlimited
  • Interspecies Interactions Unlimited
  • Ecosystem Stability Critical Transitions and Biodiversity Unlimited
  • Dynamic of Populations in Space Unlimited
  • The Neutral Theory of Ecology Unlimited

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Instructor

Massachusetts Institute of Technology
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