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Evolution and Medicine (2015, Open Yale Courses). Instructor: Professor Stephen Stearns.
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English
English [CC]
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Description
This course is a survey of evolutionary insights that make important differences in medical research and clinical practice, including evolutionary mechanisms and the medical issues they affect. Individual genetic variation in susceptibility; evolutionary conflicts and tradeoffs in reproductive medicine; the evolution of antibiotic resistance and virulence in pathogens; emerging diseases; the evolution of aging; cancer as an evolutionary process.
Course content
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- Lecture 1.1 – Natural Selection Unlimited
- Lecture 1.2 – Random Evolution, The Role of Chance Unlimited
- Lecture 1.3 – Mismatch, a Major Cause of Maladaptation Unlimited
- Lecture 1.4 – Adaptation: Why it is Problematic and How to Recognize it Unlimited
- Lecture 1.5 – Styles of Thought: Typological Thinking, Population Thinking, Tree Thinking Unlimited
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- Lecture 2.1 – Ancient History with Medical Consequences Unlimited
- Lecture 2.2 – Recent History with Medical Consequences Unlimited
- Lecture 2.3 – Genetic Variation for Disease Resistance Unlimited
- Lecture 2.4 – Genetic Variation for Ability to Metabolize Drugs Unlimited
- Lecture 2.5 – The Human Life History and its Evolution Unlimited
- Lecture 2.6 – A Patient is a Point on a Reaction Norm Unlimited
- Lecture 2.7 – Patients are Bundles of Tradeoffs Unlimited
- Lecture 2.8 – A Patient is Someone who Ages Unlimited
- Lecture 2.9 – Patients Have an Unusual Life History Unlimited
- Lecture 2.10 – The Developmental Origins of Health and Disease Unlimited
- Lecture 2.11 – The Developmental Origins of the Microbiota Unlimited
- Lecture 2.12 – Recap Unlimited
- Lecture 3.1 – Classifications of Disease Unlimited
- Lecture 3.2 – Tissues and Organs: from Vulnerable to Robust Unlimited
- Lecture 3.3 – From Fixed to Adjustable Functions Unlimited
- Lecture 3.4 – The Changing Nature of Disease Unlimited
- Lecture 5.1 – Pathogen-caused Virulence 1 Unlimited
- Lecture 5.2 – Pathogen-caused Virulence 2 Unlimited
- Lecture 5.3 – Managing the Microbiota Unlimited
- Lecture 5.4 – Evasion and Suppression Unlimited
- Lecture 5.5 – Antibiotic Resistance Unlimited
- Lecture 5.6 – Evolution-proof Therapies Unlimited
- Lecture 7.1 – Mammalian Reproduction Unlimited
- Lecture 7.2 – Invasive Placentas Unlimited
- Lecture 7.3 – Parent-offspring Conflict Unlimited
- Lecture 7.4 – Menstruation Unlimited
- Lecture 7.5 – Menopause Unlimited
- Lecture 7.6 – Upright Posture and Childbirth Unlimited
- Lecture 9.1 – Special Difficulties in Explaining Them Unlimited
- Lecture 9.2 – Drug Addiction Unlimited
- Lecture 9.3 – Extreme Expressions of Normal Behaviors Unlimited
- Lecture 9.4 – Autism and Schizophrenia Unlimited
- Lecture 11.1 – Open Questions Unlimited
- Lecture 11.2 – Differences between Classical and Evolutionary Medicine Unlimited
Instructor
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