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Principles of Human Nutrition provides an integrated overview of the physiological requirements and functions of protein, energy, and the major vitamins and minerals that are determinants of health and diseases in human populations
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Description
Course Overview
Topics include the following:- Dietary sources, intake levels, physiological role, and requirement of major nutrients.
- The biological determinants of nutrient requirements and the assessment of nutrient status in individuals and populations.
- The role of nutrition in growth and health through the life cycle.
- The rationale for the development of dietary guidelines and nutrition policies in different countries.
- The role of diet in the development of chronic diseases, such as cardiovascular disease, cancer, diabetes, etc.
Course Objectives
Upon completion of this course, you will be able to do the following:- Provide an overview of the major macro and micronutrients relevant to human health.
- Discuss the scientific rationale for defining nutritional requirements in healthy individuals and populations, with reference to specific conditions such as pregnancy, lactation, and older age.
- Present current evidence for the role of key nutrients in the prevention of chronic diseases.
- Discuss major nutrition-related diseases in a global context.
Readings
Required Reading:- J. Mann and S. Truswell (2nd edition, 2002). Essentials of Human Nutrition. Oxford University Press.
- Encyclopedia of Human Nutrition (1998). London: Academic Press.
- Shils, Olson, Shike, and Ross (Eds.), (1999). Modern Nutrition in Health and Disease, 9th edition. Williams and Wilkins.
- Linder, Ed. (1991). Nutritional Biochemistry and Metabolism, 2nd edition. Elsevier.
Textbooks
Required Reading:- J. Mann and S. Truswell (2nd edition, 2002). Essentials of Human Nutrition. Oxford University Press.
- Encyclopedia of Human Nutrition (1998). London: Academic Press.
- Shils, Olson, Shike, and Ross (Eds.), (1999). Modern Nutrition in Health and Disease, 9th edition. Williams and Wilkins.
- Linder, Ed. (1991). Nutritional Biochemistry and Metabolism, 2nd edition. Elsevier.
| Topic | Readings |
|---|---|
| Introduction | Food Science, Nutrition and Health, Fox & Cameron - Chapter 1: Food and Its Functions Recommended Dietary Allowances, NAS - Chapter 2: Definition and Applications Nutrition, ILSI - Chapter 64: Present Knowledge |
| Module 1: Energy Metabolism and Macronutrients | |
| Energy Homeostasis in Humans | WHO Technical Report No. 724 - Chapters 2 and 4 RDA, 10th Edition - Chapter 3 Jequier E, Acheson K, Schutz Y: Assessment of energy expenditure and fuel utilization in man. Ann Rev Nutr 1987; 7: 187-208. |
| Proteins and Amino Acids | Food Science, Nutrition and Health, Fox & Cameron - Chapter 9 FAO/WHO Technical Report #724 - Chapters 5 and 6 RDA 10th Edition - Chapter 6 |
| Lipids | Food Science, Nutrition and Health, Fox & Cameron - Chapter 5 Lipids: Recommended Dietary Allowances (10th edition) - Chapter 5 Garrow JS: Is there a body protein reserve? Proc Nutr Soc 1982; 41: 270-272 |
| Management of a Public Health Menace: Obesity | Pi-Sunyer FX. Obesity, in: Modern Nutrition in Health and Disease, pp 984-1006, Lea & Febiger, 1994. Cheskin, LJ Obesity, in Current Therapy in Gastroenterology and Liver Disease, pp 181-188, Mosby, 1994. |
| Protein-Energy Malnutrition | Viteri FE: Primary protein-energy malnutrition: clinical, biochemical, and metabolic changes. In: Textbook of Pediatric Nutrition. RM Suskind, editor. Raven Press, NY, 1981, pp 189-215. Picou DM: Evaluation and treatment of the malnourished child. In: Textbook of Pediatric Nutrition. RM Suskind, editor. Raven Press, NY, 1981, pp 217-228. |
| Module 2: Micronutrients | |
| Vitamin A, Vitamin E, and Carotenoids | Ross AC, Ternus ME. Vitamin A as a hormone: Recent advances in understanding the actions of retinol, retinoic acid, and beta carotene. J Am Diet Assoc 1993; 93: 1285-1290. Rock CL, Jacob RA, Bowen PE. Update on the biological characteristics of the antioxidant micronutrients: Vitamin C, vitamin E, and the carotenoids. J Am Diet Assoc 1996; 96: 693-702. Olson JA. 1992 Atwater Lecture. The irresistible fascination of carotenoids and vitamin A. Am J Clin Nutr 1993; 57: 833-839. |
| Antioxidant Nutrients | Gaziano M. Antioxidants in cardiovascular disease: randomized trials. Nutrition Reviews 54:175; 1996. Fox & Cameron: Chapter 3: Food, health and disease. Appel LJ et al. A clinical trial of the effects of dietary patterns on blood pressure. New Engl J Med 336:1117; 1997. |
| Iron and Other Hematopoietic Nutrients | Recommended Dietary Allowances, 10th ed., National Academy Press, 1989: Chapter on iron (pp. 195-205) and folate and B12 (pp. 150-165). Modern Nutrition in Health and Disease, 8th edition: Ch 9., Iron in medicine and nutrition (pp. 185-213). |
| Calcium, Phosphorus, and Vitamin D | Recommended Dietary Allowances, 10th ed., National Academy Press, 1989: Chapter on iron (pp. 195-205) and folate and B12 (pp. 150-165). Modern Nutrition in Health and Disease, 8th edition: Ch 9., Iron in medicine and nutrition (pp. 185-213). |
| Iodine | No readings assigned |
| Dietary Supplements and Fortified Foods | No readings assigned |
| Module 3: Maternal and Infant Nutrition | |
| Maternal Nutrition | No readings assigned |
| Fetal Nutrition | No readings assigned |
| Growth and Nutrition during Infancy | No readings assigned |
Course content
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- Lecture 1: Introduction 00:55:00
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- Lecture 2: Energy Homeostasis in Humans 00:55:00
- Lecture 3: Proteins and Amino Acids 00:55:00
- Lecture 4: Lipids 01:00:00
- Lecture 5: Management of Public Health Menace: Obesity 00:55:00
- Lecture 6: Protein-Energy Malnutrition 00:55:00
- Lecture 8: Antioxidant Nutrients 00:55:00
- Lecture 12: Dietary Supplements and Fortified Foods 00:55:00
Instructor
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