Topics include microstructural effects on fracture in metals, ceramics, polymers, thin films, biological materials and composites, toughening mechanisms, crack growth resistance and creep fracture. Also covered: interface fracture mechanics, fatigue damage and dislocation substructures in single crystals, stress- and strain-life approach to fatigue, fatigue crack growth models and mechanisms, variable amplitude fatigue, corrosion fatigue and case studies of fracture and fatigue in structural, bioimplant, and microelectronic components.