CHEM 125A: Freshman Organic Chemistry I (Fall 2008, Open Yale Courses). Instructor: Professor J. Michael McBride.

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September 23, 2023

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Description

CHEM 125A: Freshman Organic Chemistry I (Fall 2008, Open Yale Courses). Instructor: Professor J. Michael McBride.

This is the first semester in a two-semester introductory course focused on current theories of structure and mechanism in organic chemistry, their historical development, and their basis in experimental observation. The course is open to freshmen with excellent preparation in chemistry and physics, and it aims to develop both taste for original science and intellectual skills necessary for creative research. (from oyc.yale.edu)

Course Curriculum

  • Lecture 01 – How do You Know? Unlimited
  • Lecture 02 – Force Laws, Lewis Structures and Resonance Unlimited
  • Lecture 03 – Double Minima, Earnshaw’s Theorem, and Plum-Puddings Unlimited
  • Lecture 04 – Coping with Smallness and Scanning Probe Microscopy Unlimited
  • Lecture 05 – X-Ray Diffraction Unlimited
  • Lecture 06 – Seeing Bonds by Electron Difference Density Unlimited
  • Lecture 07 – Quantum Mechanical Kinetic Energy Unlimited
  • Lecture 08 – One-Dimensional Wave Functions Unlimited
  • Lecture 09 – Chladni Figures and One Electron Atoms Unlimited
  • Lecture 10 – Reality and the Orbital Approximation Unlimited
  • Lecture 11 – Orbital Correction and Plum-Pudding Molecules Unlimited
  • Lecture 12 – Overlap and Atom-Pair Bonds Unlimited
  • Lecture 13 – Overlap and Energy-Match Unlimited
  • Lecture 14 – Checking Hybridization Theory with XH3 Unlimited
  • Lecture 15 – Chemical Reactivity: SOMO, HOMO, and LUMO Unlimited
  • Lecture 16 – Recognizing Functional Groups Unlimited
  • Lecture 17 – Reaction Analogies and Carbonyl Reactivity Unlimited
  • Lecture 18 – Amide, Carboxylic Acid and Alkyl Lithium Unlimited
  • Lecture 19 – Oxygen and the Chemical Revolution (Beginning to 1789) Unlimited
  • Lecture 20 – Rise of the Atomic Theory (1790-1805) Unlimited
  • Lecture 21 – Berzelius to Liebig and Wohler (1805-1832) Unlimited
  • Lecture 22 – Radical and Type Theories (1832-1850) Unlimited
  • Lecture 23 – Valence Theory and Constitutional Structure (1858) Unlimited
  • Lecture 24 – Determining Chemical Structure by Isomer Counting (1869) Unlimited
  • Lecture 25 – Models in 3D Space (1869-1877); Optical Isomers Unlimited
  • Lecture 26 – Van’t Hoff’s Tetrahedral Carbon and Chirality Unlimited
  • Lecture 27 – Communicating Molecular Structure in Diagrams and Words Unlimited
  • Lecture 28 – Stereochemical Nomenclature; Racemization and Resolution Unlimited
  • Lecture 29 – Preparing Single Enantiomers and the Mechanism of Optical Rotation Unlimited
  • Lecture 30 – Esomeprazole as an Example of Drug Testing and Usage Unlimited
  • Lecture 31 – Preparing Single Enantiomers and Conformational Energy Unlimited
  • Lecture 32 – Stereotopicity and Baeyer Strain Theory Unlimited
  • Lecture 33 – Conformational Energy and Molecular Mechanics Unlimited
  • Lecture 34 – Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes Unlimited
  • Lecture 35 – Understanding Molecular Structure and Energy Through Standard Bonds Unlimited
  • Lecture 36 – Bond Energies, the Boltzmann Factor and Entropy Unlimited
  • Lecture 37 – Potential Energy Surfaces, Transition State Theory and Reaction Mechanism Unlimited

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