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This course focuses on contributions of biochemistry toward an understanding of the structure and functioning of organisms, tissues, and cells.

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2

English

English [CC]

FREE

Description

Topics include:

  • Chemistry and functions of constituents of cells and tissues and the chemical and physical-chemical basis for the structures of nucleic acids, proteins, and carbohydrates.
  • Basic enzymology and biochemical reaction mechanisms involved in macromolecular synthesis and degradation, signaling, transport, and movement.
  • General metabolism of carbohydrates, fats, and nitrogen-containing materials such as amino acids, proteins, and related compounds.

NOTE: The first half of this course, taught by Prof. Yaffe, is available on the MITx platform as 7.05x Biochemistry: Biomolecules, Methods, and Mechanisms. This OCW website provides content primarily from the second half with Prof. Vander Heiden, which focuses on metabolism.

Course content

  • Carbohydrates/Introduction to Membranes Unlimited
  • Introduction to Metabolism/Polysaccharides/Bioenergetics/Intro Pathways Unlimited
  • Bioenergetics/Intro Pathways/Glycolysis I Unlimited
  • Glycolysis II/Regulation Unlimited
  • Glucogenesis/Carbohydrate Storage/TCA Cycle I Unlimited
  • TCA Cycle II Unlimited
  • Lipids and Fatty Acid Oxidation Unlimited
  • Oxidative Phosphorylation Unlimited
  • Oxidative Phosphorylation/Photosynthesis I Unlimited
  • Photosynthesis II/CO2 Assimilation Unlimited
  • Pentose Phosphate Pathway Unlimited
  • Lipid Synthesis Unlimited
  • Nitrogen/Amino Acid Metabolism I Unlimited
  • Amino Acid Metabolism II Unlimited
  • Nucleotide Metabolism Unlimited

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Instructor

Massachusetts Institute of Technology
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