We will examine how some firms make IT a strategic asset while other firms struggle to realize value from IT investments. The course focuses on the implications of increased digitization for defining business strategies and operating models, and explores the roles of both general managers and IT executives in using IT to achieve operational excellence and business agility. Topics include business operating models, IT investment and prioritization, business strategy and IT alignment, the design and governance of digitized processes, and the role of the IT unit. Draws heavily on research and case studies from MIT Sloan Center for Information Systems Research. Restricted to graduate students.