Solvent Exposure Hazards

Health hazards associated with solvents include exposure by the following routes:

• Inhalation of a solvent may cause bronchial irritation, dizziness, central nervous system depression, nausea, headache, coma, or death. Prolonged exposure to excessive concentrations of solvent vapors may cause liver or kidney damage. The consumption of alcoholic beverages can enhance these effects.
• Skin contact with solvents may lead to defatting, drying, and skin irritation.
• Ingestion of a solvent may cause severe toxicological effects. Seek medical attention immediately.

The odor threshold for the following chemicals exceeds acceptable exposure limits. Therefore, if you can smell it, you may be overexposed — increase ventilation immediately.

• Chloroform
• Benzene
• Carbon tetrachloride
• Methylene chloride

NOTE: Do not depend on your sense of smell alone to know when hazardous vapors are present. The odor of some chemicals is so strong that they can be detected at levels far below hazardous concentrations (e.g., xylene).

In addition, some solvents (e.g., benzene) are known or suspected carcinogens.

Reducing Solvent Exposure

To decrease the effects of solvent exposure, substitute hazardous solvents with less toxic or hazardous solvents whenever possible. For example, use hexane instead of diethyl ether, benzene or a chlorinated solvent.

NOTE: The best all-around solvent is water; use it whenever possible.

The following table outlines possible solvent substitutions: