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This course, Intracellular transport, explains the function of the cytoskeleton and its role in controlling transport of vesicles between different subcellular compartments.
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English [CC]
FREE
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Description
Course learning outcomes
After studying this course, you should be able to:
- Define and use each of the terms printed in bold in the text
- Describe the characteristics of different intracellular compartments with respect to their structure, location and composition within a mammalian cell
- Describe the traffic pathways between the endoplasmic reticulum, the Golgi apparatus, the endosomal compartments, and the basolateral and apical regions of the plasma membrane
- Give examples of regulated and unregulated secretion, the mechanisms controlling the processes, and their functional significance
- Give examples of endocytosis, the mechanisms involved and their functional significance.
Course content
- Introduction 00:10:00
- Learning outcomes 00:10:00
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- Microtubules and microfilaments 00:20:00
- Polymerisation and depolymerisation of actin 00:40:00
- Polymerisation and depolymerisation of tubulin 00:30:00
- Specialised intermediate filaments 00:30:00
- Summary 00:15:00
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- Introduction 00:35:00
- Traffic in the endoplasmic reticulum and the Golgi network 00:20:00
- Sorting for the basolateral and apical zones of the plasma membrane 00:20:00
- Exocytosis and the secretory pathways 00:30:00
- The endocytic pathways and lysosomes 00:25:00
- Transcytosis 00:25:00
- Summary 00:10:00
- Introduction 00:45:00
- Formation of clathrin and COP-coated vesicles 00:50:00
- Fusion of vesicles with the target membrane 00:50:00
- The function of Rab proteins in directing traffic 00:25:00
- Cycling and re-use of membranes and traffic proteins 00:45:00
- Membrane fusion mediated by viral proteins 00:25:00
- Summary 00:15:00
- The role of the cytoskeleton in intracellular transport 00:15:00
- Motor proteins 00:50:00
- Summary 00:10:00
- Introduction 00:25:00
- Triggering systems 00:30:00
- Regulation of secretion 00:25:00
- Summary 00:10:00
- Conclusion 00:03:00
Instructor
OpenCoursa
Accessible Education for Everyone
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