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This course develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena over a range of length scales.
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English
English [CC]
FREE
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Description
Topics include: structure of tissues and the molecular basis for macroscopic properties; chemical and electrical effects on mechanical behavior; cell mechanics, motility and adhesion; biomembranes; biomolecular mechanics and molecular motors. Experimental methods for probing structures at the tissue, cellular, and molecular levels will also be investigated.
This course was originally co-developed by Professors Alan Grodzinsky, Roger Kamm, and L. Mahadevan.
Course content
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- Length, Time and Forces in Biology Unlimited
- Thermodynamics and Elementary Statistical Mechanics Unlimited
- Ideal Polymer Chains and Entropic Elasticity Unlimited
- Persistent Chain Model and Cooperativity Unlimited
- Mechano-Chemistry Unlimited
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- Composition and Structure of the Extracellular Matrix (ECM) Unlimited
- Elastic (Time-Independent) Behavior of Tissues Unlimited
- Isotropic Cross-linked Gels Unlimited
- Viscoelastic (Time-Dependent) Behavior of Tissues Unlimited
- Viscoelastic (Time-Dependent) Behavior of Tissues (cont.) Unlimited
- Poroelastic (Time-Dependent) Behavior of Tissues Unlimited
- Poroelastic (Time-Dependent) Behavior of Tissues (cont.) Unlimited
- Electromechanical and Physicochemical Properties of Tissues Unlimited
- Muscle Constriction From the Molecular to Macro Scale Unlimited
- Structure of the Cell Unlimited
- Biomembranes Unlimited
- The Cytoskeleton Unlimited
- The Cytoskeleton (cont.) Unlimited
- Cell Migration and Mechanotransduction Unlimited
Instructor
Massachusetts Institute of Technology
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