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Last updated:

October 17, 2022

Duration:

Unlimited Duration

FREE

This course includes:

Unlimited Duration

Badge on Completion

Certificate of completion

Unlimited Duration

Description

This course develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena over a range of length scales

Topics include: structure of tissues and the molecular basis for macroscopic properties; chemical and electrical effects on mechanical behavior; cell mechanics, motility and adhesion; biomembranes; biomolecular mechanics and molecular motors. Experimental methods for probing structures at the tissue, cellular, and molecular levels will also be investigated.

This course was originally co-developed by Professors Alan Grodzinsky, Roger Kamm, and L. Mahadevan.

Course Curriculum

    • Length, Time and Forces in Biology Unlimited
    • Thermodynamics and Elementary Statistical Mechanics Unlimited
    • Ideal Polymer Chains and Entropic Elasticity Unlimited
    • Persistent Chain Model and Cooperativity Unlimited
    • Mechano-Chemistry Unlimited
    • Composition and Structure of the Extracellular Matrix (ECM) Unlimited
    • Elastic (Time-Independent) Behavior of Tissues Unlimited
    • Examples Unlimited
    • Viscoelastic (Time-Dependent) Behavior of Tissues Unlimited
    • Viscoelastic (Time-Dependent) Behavior of Tissues (cont.) Unlimited
    • Poroelastic (Time-Dependent) Behavior of Tissues Unlimited
    • Poroelastic (Time-Dependent) Behavior of Tissues (cont.) Unlimited
    • Electromechanical and Physicochemical Properties of Tissues Unlimited
    • Muscle Constriction From the Molecular to Macro Scale Unlimited
    • Structure of the Cell Unlimited
    • Biomembranes Unlimited
    • The Cytoskeleton Unlimited
    • The Cytoskeleton (cont.) Unlimited
    • Cell Migration and Mechanotransduction Unlimited

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Massachusetts Institute of Technology
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