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September 23, 2023

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Description

Physics of Biological Systems. Instructor: Prof. Mithun Mitra, Department of Physics, IIT Bombay.

The application of physical principles to biological systems is an exciting and rapidly evolving field of research. Methods of equilibrium and non-equilibrium statistical physics, stochastic processes, nonlinear dynamics and polymer physics, among others have helped understand the guiding principles of a variety of biological processes. In this course, we will attempt to provide an introduction to the physics of biological systems using theoretical tools, with examples from diverse areas of biology such as pattern formation, low Reynolds number flows, cytoskeleton and motors and transport in cells, gene expression and chromatin organisation, among others. (from nptel.ac.in)

Course Curriculum

  • Lecture 01 – Introduction Unlimited
  • Lecture 02 – DNA Packing and Structure Unlimited
  • Lecture 03 – Shape and Function Unlimited
  • Lecture 04 – Numbers and Sizes Unlimited
  • Lecture 05 – Spatial Scales and System Variation Unlimited
  • Lecture 06 – Timescales in Biology Unlimited
  • Lecture 07 – Random Walks and Passive Diffusion Unlimited
  • Lecture 08 – Random Walks to Model Biology Unlimited
  • Lecture 09 – Derivation of FRAP Equations Unlimited
  • Lecture 10 – Drift-Diffusion Equations Unlimited
  • Lecture 11 – Solutions of the Drift-Diffusion Equations Unlimited
  • Lecture 12 – The Cell Signaling Problem Unlimited
  • Lecture 13 – Cell Signaling and Capture Probability of Absorbing Sphere Unlimited
  • Lecture 14 – Capture Probability of Reflecting Sphere Unlimited
  • Lecture 15 – Mean Capture Time Unlimited
  • Lecture 16 – Introduction to Fluids, Viscosity and Reynolds Number Unlimited
  • Lecture 17 – Introduction to the Navier-Stokes Equation Unlimited
  • Lecture 18 – Understanding Reynolds Number Unlimited
  • Lecture 19 – Life at Low Reynolds Number Unlimited
  • Lecture 20 – Various Phenomena at Low Reynolds Number Unlimited
  • Lecture 21 – Bacterial Flagellar Motion Unlimited
  • Lecture 22 – Rotating Flagellum Unlimited
  • Lecture 23 – Energy and Equilibrium Unlimited
  • Lecture 24 – Binding Problems Unlimited
  • Lecture 25 – Transcription and Translation Unlimited
  • Lecture 26 – Internal States of Macromolecules Unlimited
  • Lecture 27 – Protein Modification Problem Unlimited
  • Lecture 28 – Haemoglobin-Oxygen Binding Problem Unlimited
  • Lecture 29 – Freely Jointed Polymer Model Unlimited
  • Lecture 30 – Entropic Strings and Persistence Length Unlimited
  • Lecture 31 – Freely Rotating Chain Model and Radius of Gyration Unlimited
  • Lecture 32 – The Hierarchical Chromatin Packing Model Unlimited
  • Lecture 33 – FISH and DNA Looping Unlimited
  • Lecture 34 – Nucleosomes as Barriers, Hi-C, and Contact Probabilities Unlimited
  • Lecture 35 – Deriving the Full Force Extension Curve Unlimited
  • Lecture 36 – Random Walk Models for Proteins Unlimited
  • Lecture 38 – Diffusion in Crowded Environments Unlimited
  • Lecture 39 – Depletion Interactions Unlimited
  • Lecture 40 – Examples and Implications of Depletion Interactions Unlimited
  • Lecture 41 – Introduction to Biological Dynamics Unlimited
  • Lecture 42 – Introduction to Rate Equations Unlimited
  • Lecture 43 – Separation of Timescales in Enzyme Kinetics Unlimited
  • Lecture 44 – Structure and Treadmilling of Actin and Microtubules Unlimited
  • Lecture 45 – Average Length of Polymers in Equilibrium Unlimited
  • Lecture 46 – Growth Rate of Polymers Unlimited
  • Lecture 47 – Dynamic Treadmilling in Microtubules Unlimited
  • Lecture 48 – Introduction to Molecular Motors Unlimited
  • Lecture 49 – Force Generation by Molecular Motors Unlimited
  • Lecture 50 – Models of Motor Motion Unlimited
  • Lecture 51 – Molecular Motors Unlimited
  • Lecture 52 – Free Energies of Motor for Stepping Unlimited
  • Lecture 53 – Two State Models Unlimited
  • Lecture 54 – Cooperative Transport of Cargo Unlimited
  • Lecture 55 – Cytoskeleton as a Motor Unlimited
  • Lecture 56 – Translocation Ratchet Unlimited
  • Lecture 57 – Spatial Pattern in Biology Unlimited
  • Lecture 58 – Some Common Spatial Patterns in Biology Unlimited
  • Lecture 59 – Reaction Diffusion and Spatial Pattern Unlimited
  • Lecture 60 – Pattern Formation in Reaction Diffusion System with Stability Unlimited
  • Lecture 61 – Condition for Destabilization in Pattern Formation Unlimited
  • Lecture 62 – Schnakenberg Kinetics Unlimited

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