In this seminar course, the instructors will examine our current understanding of the CMB region from integrated seismological, mineral physics and geodynamical perspectives. Instructors will also introduce state-of-the-art methodologies that are employed to characterize the CMB region and relevant papers will be discussed in class. Topics will include CMB detection and topography, D’’ anisotropy, seismic velocity anomalies (e.g., ultra-low velocity zones), temperature, chemical reactions, phase relations, and mineral fabrications at the core-mantle boundary. These results will be integrated to address the CMB’s fundamental role in both mantle and core dynamics.