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Last updated:
September 21, 2023
Duration:
Unlimited Duration
FREE
This course includes:
Unlimited Duration
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Description
7.81J Systems Biology (Fall 2014, MIT OCW). Instructor: Professor Jeff Gore.
This course provides an introduction to cellular and population-level systems biology with an emphasis on synthetic biology, modeling of genetic networks, cell-cell interactions, and evolutionary dynamics. Cellular systems include genetic switches and oscillators, network motifs, genetic network evolution, and cellular decision-making. Population-level systems include models of pattern formation, cell-cell communication, and evolutionary systems biology. (from ocw.mit.edu)
Course Curriculum
- Lecture 01 – Introduction to the Class and Overview of Topics Unlimited
- Lecture 02 – Input Function, Michaelis-Menten kinetics, and Cooperativity Unlimited
- Lecture 03 – Autoregulation, Feedback and Bistability Unlimited
- Lecture 04 – Synthetic Biology and Stability Analysis in the Toggle Switch Unlimited
- Lecture 05 – Oscillatory Genetic Networks Unlimited
- Lecture 06 – Graph Properties of Transcription Networks Unlimited
- Lecture 07 – Feed-forward Loop Network Motif Unlimited
- Lecture 08 – Introduction to Stochastic Gene Expression Unlimited
- Lecture 09 – Causes and Consequences of Stochastic Gene Expression Unlimited
- Lecture 10 – Stochastic Modeling Unlimited
- Lecture 11 – Life at Low Reynolds Number Unlimited
- Lecture 12 – Robustness and Bacterial Chemotaxis Unlimited
- Lecture 13 – Robustness in Development and Pattern Formation Unlimited
- Lecture 14 – Microbial Evolution Experiments and Optimal Gene Circuit Design Unlimited
- Lecture 15 – Evolution in Finite Populations Unlimited
- Lecture 16 – Clonal Interference and the Distribution of Beneficial Mutations Unlimited
- Lecture 17 – Fitness Landscapes and Sequence Spaces Unlimited
- Lecture 18 – Evolutionary Games Unlimited
- Lecture 19 – Survival in Fluctuating Environments Unlimited
- Lecture 20 – Parasites, the Evolution of Virulence and Sex Unlimited
- Lecture 21 – Interspecies Interactions Unlimited
- Lecture 22 – Ecosystem Stability, Critical Transitions, and Biodiversity Unlimited
- Lecture 23 – Dynamics of Populations in Space Unlimited
- Lecture 24 – The Neutral Theory of Ecology Unlimited
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