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This course provides an introduction to cellular and population-level systems biology with an emphasis on synthetic biology, modeling of genetic networks, cell-cell interactions, and evolutionary dynamics.
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English
English [CC]
FREE
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Description
Cellular systems include genetic switches and oscillators, network motifs, genetic network evolution, and cellular decision-making. Population-level systems include models of pattern formation, cell-cell communication, and evolutionary systems biology.
Course content
- Introduction to the Class and Overview of Topics Unlimited
- Input Function, Michaelis-Menten Kinetics, and Cooperativity Unlimited
- Autoregulation, Feedback and Bistability Unlimited
- Synthetic Biology and Stability Analysis In the Toggle Switch Unlimited
- Oscillatory Genetic Networks Unlimited
- Graph Properties Of Transcriptions Networks Unlimited
- Feed-Forward Loop Network Motif Unlimited
- Introduction To Stochastic Gene Expression Unlimited
- Stochastic Modeling Unlimited
- Life at Low Reynolds Number Unlimited
- Robustness and Bacterial Chemotaxis Unlimited
- Robustness in Development and Pattern Formation Unlimited
- Microbial Evolution Experiments and Optimal Gene Circuit Design Unlimited
- Evolution in Finite Populations Unlimited
- Clonal Interference and the Distribution of Beneficial Mutations Unlimited
- Fitness and Landscapes and Sequence Spaces Unlimited
- Evolutionary Games Unlimited
- Survival in Fluctuating Environment Unlimited
- Parasites, The Evolution of Virulence and Sex Unlimited
- Interspecies Interaction Unlimited
- Ecosystem Stability, Critical Transition, and Biodeversity Unlimited
- Dynamic of Populations in Space Unlimited
- The Natural Theory of Ecology Unlimited
Instructor
Massachusetts Institute of Technology
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